Abstract:
In a simple case of disputed paternity we will have evidence in the form of
DNA profiles from the child, mother and putative father: it is then
relatively straightforward to determine the strength of the evidence
bearing on paternity. But often the putative father is unavailable for
testing, and instead we have to make do with DNA from one or more of his
relatives. Other features, such as mutation, silent alleles, laboratory and
handling errors, etc., introduce additional complications. The task of
interpreting the forensic evidence in such cases can become extremely
challenging, both logically and computationally.
Recently it has been shown how the technology of Bayesian networks -- especially in its "object-oriented" version -- can be used to represent and solve such problems. I will describe the basics of this approach, present a collection of fundamental networks that can be flexibly combined (like a child's construction kit) to represent a very wide range of problems arising in forensic genetics, and illustrate their use in some real cases.